Research Interests
Cell Biology of the Trophoblast
The overall goal of our lab is to identify mechanisms involved in the trophoblast-endometrium dialogue during placental development, focusing mainly the role played by trophoblast in producing or responding to the specific molecular gestational repertoire at the maternal fetal interface. The main approach being taken is to use primary cultures of trophoblast (human isolated cells; mouse ectoplacental cone cells), decidual, endothelial and immune cells as model systems in which gene regulation, signaling mechanisms and biological functions relevant to physiological and patho-physiological aspects can be studied.
RELEVANT PAPERS
- Bevilacqua, E. & Abrahamsohn, P.A. Invasiveness of mouse trophoblastic cells in connective tissues. Acta Anat., 150: 246-252, 1994.
- Faria, M. & Bevilacqua, E. Cytological aspects of vascular invasion by the trophoblast of Calomys callosus in hepatic tissues. J. Morphol., 226:159-171, 1995.
- Gagioti, S.; Colepicolo, P. & Bevilacqua, E. Post-implantation mouse embryos have the capability to generate and release reactive oxygen species. Reprod. Fertil. Dev., 7:1111-1116, 1995.
- Gagioti, S.; Colepicolo, P. & Bevilacqua, E. Reactive oxygen species and the phagocytosis process of the hemochorial trophoblast. Ciência & Cultura, 48: 37-42, 1996.
- Albieri, A. & Bevilacqua, E. Effects of phorbol myristate acid and all-trans-retinal on erythrophagocytosis activity of cultured mouse trophoblast. Placenta, 17: 507-512, 1996.
