RESEARCH INTERESTS
Since 1981 when the laboratory iof Biology of Reproduction began its activities our main interest is the decidualization in mice, both natural and artificially-induced. Decidualization is a very interesting biological phenomenon because it involves transformation of endometrial fibroblasts into cells with epithelioid features. Research has been done mainly on components of the extracellular matrix, especially collagen and proteoglycans. The4se studies have used methods of light and electron microscopy associated to several techniques such as in situ autoradiography, cytochemistry, immunocytochemistry and biochemistry.
RELEVANT PAPERS
Alberto-Rincon, M.C. , Abrahamsohn, P.A. & Zorn, T.M.T. Diameter increase of collagen fibrils of the mouse endometrium during decidualization. Am. J. Anat. 186:417-429,1989.
Zorn, T.M.T., Bijovski, A.T., Bevilacqua, E.M.A.F. & Abrahamsohn, P.A. Phagocytosis of collagen by mouse decidual cells. Anat. Rec. 225:96-100,1998.
Zorn, T.M.T., Oliveira, S.F. & Abrahamsohn, P.A. Organization of intermediate filaments and their association with collagen-containing phagosomes in mouse decidual cells. J. Struct. Biol. 103:23-33,1990.
Andrade, C.G.T.J., Savino, W., Abrahamsohn, P.A. & Zorn, T.M.T. Distribution of desmoplakin I/II in endometrial cells of mice in the artificially induced decidua. Tissue & Cell 26:639-647,1994.
Greca, C.P.S., Abrahamsohn, P.A., Nader, H.D. & Zorn, T.M.T. Localization and characterization of proteoglycans in the endometrium of pregnant mice. A cytochemical ultrastructural study. Acta Histochemica and Cytochemica 29:598-600, 1996.
